• Марина Шараєва Національний медичний університет імені А.А. Богомольця


Two cases of поп-effusive pericarditis associated with serologically proven Epstein - Barr virus were reported. Almost healthy young males had complaints of abrupt onset of retrosternal chest pain that appeared during breathing or moving. Other common causes of chest pain must be ruled out, including cardiac ischemia, pneumonia, costochondritis, pulmonary embolism and substance abuse (cocaine). The past medical history were unremarkable, they denies recent use of medications. During physical exanimation a pericardial friction rub was not heard, X-ray was normal. The 2015 updated European Society of Cardiologists Guidelines for the diagnosis and management of pericardial diseases recommended ECG, Echo, measurement of inflammatory or myocardial injury markers. The presentation and discussion of ECG typical changes and Echo signs that proved diagnosis of acute pericarditis were reported. Potential causes of pericarditis are numerous and include trauma, viral infection, tuberculosis, malignant disease and autoimmune conditions. The search for causative factors is often fruitless, because the condition is deemed to be idiopathic. It is common that viruses can lead to acute pericarditis, but only few cases of EBV-associated pericarditis have been previously published. Broad serological tests of infectious diseases were taken. EBV-associated effusive or поп-effusive pericarditis may develop without any signs of the infectious mononucleosis in young and almost healthy patients. Both patients made a good physical recovery after being placed on special non-steroid anti-inflammatory drugs, colchicine therapy.


1. M. Pepi, M. Muratori: Echocardiography in the diagnosis and management of pericardial disease. Journal of Cardiovascular Medicine 2006, 7:533-544.
2. Aditya Shetty, Frank Gaillard: Pericardial effusion.
Radiopaedia. Org
3. M.LeWinter, Acute Pricardities N EnglJ Med
4. ESC Guidelines for the diagnosis and management of pericardial diseases . Eur Heart J 2015; 36;42: 2921-2964
5. Spodick DH. Acute pericarditis: current concepts and practice. JAMA. 2003;289:1150.
6. Baljepally R, Spodick DH. PR-segment deviation as the initial electrocardiographic response in acute pericarditis. Am J Ca rdiol. 1998;81:1505-6.
7. Zayas R, Anguita M, Torres F, et al. Incidence of specific etiology and role of methods for specific etiologic diagnosis of primary acute pericarditis. Am J Cardiol 1995;75:378-82
8. Mijailovic Z, Canovic P, Gajovic O, Tomas evic S: Myopericarditis during acute Epstein -Barr virus infection: a case report. Medicinski pregled 2006; 59: 490 - 493.
9. Lentini S., Klingel K., Skowasch D., Kandolf R., Bauriedel G.: Epstein - Barr virus - associated pericarditis. Deutsch Med Wochenscher 2001 Sep 21; 126 (39): 1043-1046.
10. Акрек M., Yarlioglues M., Durmaz S., Kaya MG.: Pericardial tamponanade associated with Epstein - Barr virus in an Immunocompetent young patient. Turk Kardiyol Dem Ars 2011 Jul; 39 (5): 407-409.
11. B. Zafrir, A. Aviv, N.Reichman, E. Flatau: Epstein - Barr virus - associated pericarditis and pericardial effusion: case report and diagnostic aspects. European Journal of Internal Medicine 2005; 16: 528 -530
12. F. RoubiUe, G. Gahide, T. Moore -Morris, M. Granier, J - M. Davy, H. Vernhet, C. Piot: Epstein - Barr virus (EBV) and acute myopericarditis in an immunocompetent patient: first demonstrated case and discussion. Internal Medicine 2008; 47: 627 -629.
13. Imazio M, Demichelis B, Parrini I, et al. Day-hospital treatment of acute pericarditis: a management program for outpatient therapy. J Am Coll Cardiol 2004;43:1042-6.
Як цитувати
Шараєва, М. (1). ГОСТРИЙ ПЕРИКАРДИТ, АСОЦІЙОВАНИЙ З ЕПШТЕЙН-БАРР ВІРУСОМ: ДВА ВИПАДКИ. Український науково-медичний молодіжний журнал, 4(91), 38-42. вилучено із http://mmj.nmuofficial.com/index.php/journal/article/view/191