РОЛЬ ХІРУРГІЧНОГО ЛІКУВАННЯ У ХВОРИХ НА ПЕРВИННО-МЕТАСТАТИЧНИЙ РАК МОЛОЧНОЇЗАЛОЗИ
Ключові слова:
первинно-розповсюджений ракочної залози, хірургічне лікування, виживаність
Анотація
Резюме. В роботі проведено порівняльний аналіз результатів комплексного лікування хворих на первинно поширений рак молочної залози з та без оперативного втручання. В двох группах хворих проводили комплексне паліативне лікування, яке включало променеву терапію, хіміотерапію, гормональну терапію (група 1-79 хворих) і в дослідній групі (група 2-42 хворі) лікування ще включало операцію - видалення первинного вогнища. Досліджена виживаності хворих за методом Каплан-Майєра показало більшу виживаність хворих в групі з хірургічним лікуванням. 3-х та 5-ти річна виживаність була більша на 29% и 26% відповідно, а медіана виживаності - на 11 місяців. В групі з хірургічним лікуванням проведення передопераційного спеціального лікування покращило 3-х та 5-ти річну виживаність на 20% та 10%, а також медіану виживаності на 14 міс.
Посилання
1. Бюллетень Национального канцер-регистра№ 11 - "Рак в Украине, 2008-2009", Киев — 2010
2. Wood WC, Muss НВ, Solin LJ, et al: Cancer of the breast, in DeVita VT Jr, Hellman S, Rosenberg SA (eds): Cancer Principles & Practice of Oncology’. Philadelphia, PA, Lippincott Williams & Wilkins, 2005, pp 1453-1462
3. Lee, CG, McCormick, B, Mazumdar, M, et al. Infiltrating breast carcinoma in patients age 30 years and younger: long term outcome for life, relapse, and second primary tumors. Int JRadiat Oncol Biol Phys 1992: 23:969.
4. Vogel, CL, Azevedo, S, Hilsenbeck, S, et al. Survival after first recurrence of breast cancer The Miami experience. Cancer 1992; 70:129.
5. Bernard-Marty C, Cardoso F, Piccart MJ: Facts and controversies in systemic treatment of metastatic breast cancer Oncologist 2004; 9:617-632.
6. Hortobagyi GN: Treatment of breast cancer N Engl J Med 1998; 339:974-984.
7. Coffey JC, Wang JH, Smith MJ, et al: Excisional surgery for cancer cure: Therapy at a cost. Lancet Oncol 2003; 4:760-768.
8. Baum M, Demicheli R, Hrushesky W, et al: Does surgery unfavourably perturb the "natural history " of early breast cancer by accelerating the appearance of distant metastases? Eur J Cancer 2005; 41:508-515.
9. National Health and Medical Research Council: Clinical practice guidelines for the management ofadvanced breast cancer Prepared by the iSource National Breast Cancer Centre Advanced Breast Cancer Working Group. Endorsed January 2001. www.nhmrc.gov.au/publications/ synopses/cp76syn. htm
10. National Cancer Institute: Breast Cancer (PDQ): Treatment. Stage IIIB, inoperable НІС, IV, recurrent, and metastatic breast cancer www.cancer.gov/cancertopics/pdq/ treatment/breast/HealthProfessional/page8
11. Canadian Cancer Society: Canadian Cancer Encyclopedia. Breast cancer Treatment by stage. Stage IV breast cancer—treatment. Stage IV (any T, anyN, Ml), http:/ /info.cancerca/E/CCE/cceexplorerascp?tocid= 10
12. Babiera GV, Rao R, Feng L, et al. Effect ofprimary tumor extirpation in breast cancer patients who present with stage IV disease and an intact primary tumor. Ann Surg Oncol 2006;13:776-782.
13. В afford AC, Burstein HJ, Barkley CR, et al. Breast surgery in stage IV breast cancer: impact of staging and patient selection on overall survival. Breast Cancer Res Treat 2009;115:7-12.
14. Blanchard DK, Shetty PB, Hilsenbeck SG, et al. Association o f surgery with improved survival in stage IV breast cancer patients. Ann Surg 2008;247(5):732-738.
15. Cady B, Nathan NR, Michaelson JS, et al. Matched pair analyses of stage IV breast cancer with or without resection o f primary breast site. Ann Surg Oncol 2008;l 5:3384-3395.
16. Fields RC, Jeffe DB, Trinkaus K, et al. Surgical resection of the primary tumor is associated with increased long-term survival in patients with stage IV breast cancer after controlling for site of metastasis. Ann Surg Oncol 2007;14:3345-3351.
17. Gnerlich J, Jeffe DB, Deshpande AD, et al. Surgical removal of the primary tumor increases overall survival in patients with metastatic breast cancer: analysis of the 1988- 2003 SEER data. Ann Surg Oncol 2007;14:2187-2194.
18. Hazard HW, Gorla SR, Kim J, Scholtens D. Surgical resection of the primary tumor in stage IV breast cancer and survival. Society of Surgical Oncology’ (SSO). 60th annual cancer symposium. Cancer 2008;113:2011-2019.
19. Khan SA, Stewart AK, Morrow M. Does aggressive local therapy improve survival in metastatic breast cancer? Surgery 2002;132:620-626.
20. Rao R, Feng L, Kuerer HM, et al. Timing of surgical intervention for the intact primary in stage IV breast cancer patients. Ann Surg Oncol 2008; 15:1696-1702.
21 .Rapiti E, Verkooijen HM, Vlastos G, etal. Complete excision of primary breast tumor improves survival of patients with metastatic breast cancer at diagnosis. J Clin Oncol 2006;24:2743-2749.
22. Ruiterkamp J, Ernst MF, van de Poll-Franse LV, et al. Surgical resection of the primary tumour is associated with improved survival in patients with distant metastatic breast cancer at diagnosis. Eur JSurg Oncol 2009; 35(11):1146-1151.
23. Shien T, Kinoshita T, Shimizu C, et al. Primary tumor resection improves the survival of younger patients with metastatic breast cancer. Oncol Rep 2009;21:827-832.
24. Leung AM, Vu HN, Nguyen KA, et al. Effects of surgical excision on survival of patients with stage IV breast cancer. J Surg Res 2010;161(l):83-88.
25. Sobin LH, Wittekind C, editors. TNM classification of malignant tumours. 5th ed. UICC International Union Against Cancer. New York: Wiley-Liss, 1997.
26. Flanigan RC, Salmon SE, Blumenstein BA, et al: Nephrectomy followed by interferon alfa-2b compared with interferon alfa-2b alone for metastatic renal-cell cancer. N Engl J Med 345:1655-1659, 2001
27. Rosen SA, Buell JF, Yoshida A, et al: Initial presentation with stage IV colorectal cancer: How aggressive should we be? Arch Surg 135:530-534, 2000
28. Hallissey MT, Allum WH, Roginski C, et al: Palliative surgery for gastric cancer. Cancer 62:440-444, 1988
29. Essner R, Lee JH, Wanek LA, et al: Contemporary surgical treatment of advanced-stage melanoma. Arch Surg 139:961-966, 2004
30. Cristofanilli M, Budd GT, Ellis MJ, et al: Circulating tumor cells, disease progression, and survival in metastatic breast cancer. N Engl J Med 351:781-791, 2004
31. Cristofanilli M, Hayes DF, Budd GT, et al: Circulating tumor cells: A novel prognostic factor for newly diagnosed metastatic breast cancer. J Clin Oncol 23:1420- 1430, 2005
2. Wood WC, Muss НВ, Solin LJ, et al: Cancer of the breast, in DeVita VT Jr, Hellman S, Rosenberg SA (eds): Cancer Principles & Practice of Oncology’. Philadelphia, PA, Lippincott Williams & Wilkins, 2005, pp 1453-1462
3. Lee, CG, McCormick, B, Mazumdar, M, et al. Infiltrating breast carcinoma in patients age 30 years and younger: long term outcome for life, relapse, and second primary tumors. Int JRadiat Oncol Biol Phys 1992: 23:969.
4. Vogel, CL, Azevedo, S, Hilsenbeck, S, et al. Survival after first recurrence of breast cancer The Miami experience. Cancer 1992; 70:129.
5. Bernard-Marty C, Cardoso F, Piccart MJ: Facts and controversies in systemic treatment of metastatic breast cancer Oncologist 2004; 9:617-632.
6. Hortobagyi GN: Treatment of breast cancer N Engl J Med 1998; 339:974-984.
7. Coffey JC, Wang JH, Smith MJ, et al: Excisional surgery for cancer cure: Therapy at a cost. Lancet Oncol 2003; 4:760-768.
8. Baum M, Demicheli R, Hrushesky W, et al: Does surgery unfavourably perturb the "natural history " of early breast cancer by accelerating the appearance of distant metastases? Eur J Cancer 2005; 41:508-515.
9. National Health and Medical Research Council: Clinical practice guidelines for the management ofadvanced breast cancer Prepared by the iSource National Breast Cancer Centre Advanced Breast Cancer Working Group. Endorsed January 2001. www.nhmrc.gov.au/publications/ synopses/cp76syn. htm
10. National Cancer Institute: Breast Cancer (PDQ): Treatment. Stage IIIB, inoperable НІС, IV, recurrent, and metastatic breast cancer www.cancer.gov/cancertopics/pdq/ treatment/breast/HealthProfessional/page8
11. Canadian Cancer Society: Canadian Cancer Encyclopedia. Breast cancer Treatment by stage. Stage IV breast cancer—treatment. Stage IV (any T, anyN, Ml), http:/ /info.cancerca/E/CCE/cceexplorerascp?tocid= 10
12. Babiera GV, Rao R, Feng L, et al. Effect ofprimary tumor extirpation in breast cancer patients who present with stage IV disease and an intact primary tumor. Ann Surg Oncol 2006;13:776-782.
13. В afford AC, Burstein HJ, Barkley CR, et al. Breast surgery in stage IV breast cancer: impact of staging and patient selection on overall survival. Breast Cancer Res Treat 2009;115:7-12.
14. Blanchard DK, Shetty PB, Hilsenbeck SG, et al. Association o f surgery with improved survival in stage IV breast cancer patients. Ann Surg 2008;247(5):732-738.
15. Cady B, Nathan NR, Michaelson JS, et al. Matched pair analyses of stage IV breast cancer with or without resection o f primary breast site. Ann Surg Oncol 2008;l 5:3384-3395.
16. Fields RC, Jeffe DB, Trinkaus K, et al. Surgical resection of the primary tumor is associated with increased long-term survival in patients with stage IV breast cancer after controlling for site of metastasis. Ann Surg Oncol 2007;14:3345-3351.
17. Gnerlich J, Jeffe DB, Deshpande AD, et al. Surgical removal of the primary tumor increases overall survival in patients with metastatic breast cancer: analysis of the 1988- 2003 SEER data. Ann Surg Oncol 2007;14:2187-2194.
18. Hazard HW, Gorla SR, Kim J, Scholtens D. Surgical resection of the primary tumor in stage IV breast cancer and survival. Society of Surgical Oncology’ (SSO). 60th annual cancer symposium. Cancer 2008;113:2011-2019.
19. Khan SA, Stewart AK, Morrow M. Does aggressive local therapy improve survival in metastatic breast cancer? Surgery 2002;132:620-626.
20. Rao R, Feng L, Kuerer HM, et al. Timing of surgical intervention for the intact primary in stage IV breast cancer patients. Ann Surg Oncol 2008; 15:1696-1702.
21 .Rapiti E, Verkooijen HM, Vlastos G, etal. Complete excision of primary breast tumor improves survival of patients with metastatic breast cancer at diagnosis. J Clin Oncol 2006;24:2743-2749.
22. Ruiterkamp J, Ernst MF, van de Poll-Franse LV, et al. Surgical resection of the primary tumour is associated with improved survival in patients with distant metastatic breast cancer at diagnosis. Eur JSurg Oncol 2009; 35(11):1146-1151.
23. Shien T, Kinoshita T, Shimizu C, et al. Primary tumor resection improves the survival of younger patients with metastatic breast cancer. Oncol Rep 2009;21:827-832.
24. Leung AM, Vu HN, Nguyen KA, et al. Effects of surgical excision on survival of patients with stage IV breast cancer. J Surg Res 2010;161(l):83-88.
25. Sobin LH, Wittekind C, editors. TNM classification of malignant tumours. 5th ed. UICC International Union Against Cancer. New York: Wiley-Liss, 1997.
26. Flanigan RC, Salmon SE, Blumenstein BA, et al: Nephrectomy followed by interferon alfa-2b compared with interferon alfa-2b alone for metastatic renal-cell cancer. N Engl J Med 345:1655-1659, 2001
27. Rosen SA, Buell JF, Yoshida A, et al: Initial presentation with stage IV colorectal cancer: How aggressive should we be? Arch Surg 135:530-534, 2000
28. Hallissey MT, Allum WH, Roginski C, et al: Palliative surgery for gastric cancer. Cancer 62:440-444, 1988
29. Essner R, Lee JH, Wanek LA, et al: Contemporary surgical treatment of advanced-stage melanoma. Arch Surg 139:961-966, 2004
30. Cristofanilli M, Budd GT, Ellis MJ, et al: Circulating tumor cells, disease progression, and survival in metastatic breast cancer. N Engl J Med 351:781-791, 2004
31. Cristofanilli M, Hayes DF, Budd GT, et al: Circulating tumor cells: A novel prognostic factor for newly diagnosed metastatic breast cancer. J Clin Oncol 23:1420- 1430, 2005
Опубліковано
2010-12-29
Як цитувати
Любота, І. І., Любота, Р. В., Чешук, В. Є., Олійніченко, Г. П., & Щепотін, І. В. (2010). РОЛЬ ХІРУРГІЧНОГО ЛІКУВАННЯ У ХВОРИХ НА ПЕРВИННО-МЕТАСТАТИЧНИЙ РАК МОЛОЧНОЇЗАЛОЗИ. Український науково-медичний молодіжний журнал, 3(57), 61-64. вилучено із http://mmj.nmuofficial.com/index.php/journal/article/view/705
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