IGG4 - АСОЦІЙОВАНІ ЗАХВОРЮВАННЯ - НОВА КЛАСИФІКАЦІЙНА ОДИНИЦЯ В РЕВМАТОЛОГІЇ
Ключові слова:
ІgC4-асоційовані захворювання, аутоімунний панкреатит, хвор=оба Мікуліча, тиреоїдит Ріделя, псевдопухлина орбіт, мультифокальний фібросклероз, запальна аневризма черевної аорти, хронічний склерозуючий аортит
Анотація
Резюме. У даній статті представлені літературні дані останніх років щодо нової класифікаційної одиниці в ревматології - 1дС4-асоційованих захворювань. Продемонстровано патогенетична роль lgG4, лигандов фактора некрозу пухлин BAFF і APRIL, Т і В-лімфоцитів, а також різних цитокінів в розвитку даної патології. Коротко викладені клінічні прояви, методи діагностики і підходи до лікування 1дС4-асоційованих захворювань.
Посилання
1. Лысенко Г.И. Новости медицины. 1§О4-связанное заболевание /Г.И. Лысенко, Л.В. Химион, Е.А. Гармиш.,
С.В. Данилюк, О.Б. Ященко // Укр. Реем. Журнал. -2013,- №2 - С. 8-13.
2. Stone J.H. IgG4-related disease / John H. Stone, Yoh Zen, Vikram Deshpande // N Engl. J Med. - 2012. - Vol. 336. - P.539-561.
3. Stone JH. lgG4-related systemic disease and lymphoplasmacytic aortitis / JH Stone, A.Khosroshahi, A.Hilgenberg et al. // Arthritis Rheum. - 2009. - Vol. 60. - P.3139-3145.
4. Frulloni L. Identification of a novel antibody associated with autoimmune pancreatitis / L.Frulloni, C. Lunar di, R. Simone, et al. // N Engl. J Med. - 2009. - Vol.361. - P.2135-2142.
5. Nishimori I. Prevalence of autoimmune pancreatitis in Japan from a nationwide survey in 2002 /I. Nishimori, A. Tama- koshi, M.Otsuki // J Gastroenterol. - 2007. - Vol.42. - P. 6-8.
6. Yamamoto M. Clinical and pathological differences between Mikulicz’s disease and Sjogren’s syndrome / M. Yamamoto, S. Harada, M. Ohara, et al // Rheumatology (Oxford) - 2005. - Vol.44. - P.227-234.
7. Stone J.H. Aortitis, retroperitoneal fibrosis, and lgG4-related disease / John H. Stone // La Presse Medicale. - 2013. - Vol.42. -P. 622-625.
8. Stone JH. lgG4-related systemic disease accounts for a significant proportion of thoracic lymphoplasmacytic aortitis cases / JH.Stone, A.Khosroshahi, VDeshpande, JR.Stone //Arthrit. Care Res.-2010. - Vol.62. -P. 316-322.
9. Stone J.H. Aortitis, periaortitis, and retroperitoneal fibrosis, as manifestations of lgG4-related systemic disea¬se / John H. Stone // Curr. Opin. Rheumatol. - 2011. - Vol.23(l). - P.88.
10. Kasashima S. A clinicopathologic study of immu¬noglobulin G4-related disease of the femoral and popliteal arteries in the spectrum of immunoglobulin G4-related periarteritis /S.Kasashima, A.Kawashima, M.Endo //Journal of Vascular Surgery. - 2010. - Vol.57. - P. 816-822.
11. Umehara H. Comprehensive diagnostic criteria for lgG4-relateddisease, 2011 /H. Umehara, K.Okazaki, Y. Ma- saki, et al //Mod. Rheumatol. - 2012. - Vol.22. - P.21-30.
12. Kamisawa T. Serum lgG4-negative autoimmune pancreatitis / T.Kamisawa, K.Takuma, T.Tabata, et al. //
J. Gastroenterol. -2011. - Vol.46. - P. 108-116.
13. Ebbo M. Pathologies associated with serum IgG4 elevation / M.Ebbo, A. Grades, E.Bernit, et al. // Int.
J. Rheumatol. - 2012. - Vol. 64. - P. 602-613.
14. Carruthers M. Diagnosyic utility of serum IgG4 concentration in lgG4-related disease [Abstract] / M.Carruthers, T.Augustin, JH.Stone, A.Khosroshahi // Arthritis Rheum 2012.
15. Sah RP. Serologic issues in lgG4-related systemic disease and autoimmune pancreatitis /RP.Sah, ST.Chari // Curr. Opin. Rheumatol. - 2011. - Vol.23. - P. 108-113.
16. Hamano H. High serum IgG4 concentrations in patients with sclerosing pancreatitis. /H.Hamano, S.Kawa, A.Horiuchi, et al. // N. Engl. J. Med. - 2001. - Vol.334. - P.732-738.
17. Zen Y. Pathophysiology of IgG4-Related Disease / Y.Zen, Y.Nakanuma // Current Immunology Reviews. -2011. - Vol. 2. -P. 232-238.
lS.Kawa S. HLA DRB10405-DQB10401 haplotype is associated with autoimmune pancreatitis in the Japanese population / S.Kawa, M.Ota, K.Yoshizawa, et al. // Gastroenterology. - 2002. - Vol. 122. - P. 1264-1269.
19. Nirula A. What is IgG4? A review of the biology of a unique immunoglobulin subtype / A.Nirula, SM.Glaser, SL.Kalled, FR.Taylor // Curr. Opin. Rheumatol. - 2011. - Vol.23. -P. 119-124.
20. Kiyama K. Serum BAFF and APRIL levels in patients with IgG4-related disease and their clinical significance / KKiyama, D.Kawabata, Y.Hosono, KKitagori, N. Yukawa, H.Yoshifuji, K. Omura, T.Fujii, T.Mimori//Arthritis Research & Therapy - 2012. - Vol. 14. - P. 86.
21. Kasashima S. A new clinicopathological entity ofIgG4- related inflammatory abdominal aortic aneurysm / S.Ka¬sashima, Y.Zen, A.Kawashima, M.Endo, YMatsumoto, F.Ka- sashima // J. Vase. Surg.-2009. - Vol.49 (5). -P. 1264-1271.
22. Kasashima S. IgG4-related Inflammatory Abdominal Aortic Aneurysm, Spectrum of IgG4-related Chronic Periaortitis /S.Kasashima, Y.Zen //Ann. Vase. Dis. -2010. - Vol. 3(3). - P. 182-189.
23. Raparia K. Inflammatory aortic aneurysm: possible manifestation of IgG4-related sclerosing disease / KRaparia, C.P.Molina, G.Quiroga Garza, D.Weilbaecher, AG.Ayala, JY.Ro //Int. J. Clin. Exp. Pathol. -2013. - Vol.6 (3). - P. 469-475.
24. Mackay F. BAFF and APRIL: a tutorial on В cell survival / F.Mackay, P.Schneider, P.Rennert, J.Browning // Ann. Rev. Immunol. - 2003. - Vol.21. - P. 231-264.
25. Koike T. IgG4-related disease: why high lgG4 and fibrosis? / T.Koike //Arthritis. Res. Ther. - 2013. - Vol. 15 (1). - P. 103.
26. Kamisawa T. Allergic manifestations in autoimmune pancreatitis / T.Kamisawa, HAnjiki, N.Egawa, N.Kubota // Eur. J. Gastroentero. Hepatol. - 2009. - Vol.21. - P. 1136- 1139.
27. Li ZZ. Pathogenesis of Abdominal Aortic Aneurysms: Role of Nicotine and Nicotinic Acetylcholine Receptors / ZZ.Li, QY.Dai //Mediators Inflamm. - 2012. - Vol.2012. - P. 103-120.
28. Inoue D. Immunoglobulin G4-related periaortitis and periarteritis: CTfindings in 17patients/D.Inoue, Y.Zen, HAbo, T.Gabata//Radiology. -2011. - Vol.261. - P. 625-633.
29. Zen Y. IgG4-related disease: a cross-sectional study of 114 cases / Y.Zen, Y.Nakanuma //Am. J. Surg. Pathol. - 2010. - Vol. 34(12). -P. 1812-1819.
30. Sato Y. Systemic IgG4-related lymphadenopathy: a clinical and pathologic comparison to multicentric Castle¬man ’s disease / Y.Sato, M.Kojima, et al. // Mod/ Pathol. -
2009. - Vol. 22(4). - P. 589-599.
31. Cheuk W. IgG4-related sclerosing disease: a critical appraisal of an evolving clinicopathologic entity / W. Cheuk, JKChan // Adv. Anat. Pathol. - 2010. - Vol. 17(5). - P. 303-332.
32. Sato Y. Association between IgG4-related disease and progressively transformed germinal centers of lymph nodes /Y.Sato, D.Inoue, et al. //Mod. Pathol. - 2012. - Vol. 25(7).- P. 956-967.
33. Yamamoto M. Evaluation and Clinical Validity of a New Questionnaire for MikuliczIs Disease / M. Yamamoto, H. Takahashi, Kdshigami, H.Yajima, etal. //Int. J. Rheumatol. - 2012. - Vol. 2012. - P. 283-289.
34. Moriyama M. T helper subsets in SjogrenIs syndrome and IgG4-related dacryoadenitis and sialoadenitis: A cri¬tical review / M.Moriyama, A. Tanaka, T.Maehara, S. Furukawa, et al. // Journal of Autoimmunity xxx (2013) le8 (in press).
35. Dasari BV IgG4-related systemic sclerosing disease: a diagnosis to be considered / BVDasari, KMcElvanna, M.Loughrey, T.Diamond // BMJ Case Rep. - 2013. - doi: 10.1136/bcr-2012-007101.
36. Maehara T. Interleukin-21 contributes to germinal centre formation and immunoglobulin G4 production in IgG4-related dacryoadenitis and sialoadenitis, so-called Mikulicz Is disease / T.Maehara, MMoriyama, H.Nakashima,
K.Miyake, JN.Hayashida, A.Tanaka, et al. //Ann. Rheum. Dis. - 2012. - Vol. 71. - P. 2011-2020.
37.Sah R.P. Differences in clinical profile and relapse rate of type 1 versus type 2 autoimmune pancreatitis. Gastroenterology /RP.Sah, STChari, R.Pannala, et al. // -
2010. - Vol. 139(1).-P. 140-148.
38. Hardacre JM. Results of pancreaticoduodenectomy for lymphoplasmacytic sclerosing pancreatitis / JM.Hardacre, CA.Iacobuzio-Donahue, TA.Sohn, et al. // Ann. Surg. - 2003. - Vol. 237. - P. 853-859.
39. Bateman AC, Deheragoda MG. IgG4-related systemic sclerosing disease-an emerging and under¬diagnosed condition. Histopathology. - 2009. - Vol. 55. - P. 373-383.
40. Ghazale A. Value of serum lgG4 in the diagnosis of autoimmune pancreatitis and in distinguishing it from pancreatic cancer /A.Ghazale, ST.Chari, TC.Smyrk, etal. // Am J Gastroenterol. - 2007. - Vol. 102(8). - P. 1646-1653.
41. Hennessey JV. Riedel’s Thyroiditis: A Clinical Review / JVHennessey // J. Clin, Endocrinol, Metab. - 2011. - Vol. 96(10). - P. 3031-3041.
42. Divatia M. IgG4-Related Sclerosing Disease, an Emerging Entity: A Review of a Multi-System Disease / M. Divatia, S.A.Kim, J. Y.Ro // Yonsei Med. J. - 2012. - Vol. 53(1). -P. 15-34.
43. Taniguchi T. Interstitial pneumonia associated with autoimmune pancreatitis / T.Taniguchi, M.Ko, SSeko, et al. // Gut. - 2004. - Vol. 53(5). - P. 770-771.
44. Zen Y. IgG4-positive plasma cells in inflammatory pseudotumor (plasma cell granuloma) of the lung / Y.Zen, S.Kitagawa, H.Minato, et al. //Hum. Pathol. - 2005. - Vol. 36(7). -P. 710.
45. Inoue D. Immunoglobulin G4-related lung disease: CT findings with pathologic correlations / D.Inoue, Y.Zen, HAbo, et al. //Radiology. - 2009. - Vol. 251. - P. 260.
46. Gopalakrishnan N. lgG4 related interstitial nephritis: A case report and review of literature / N. Gopalak¬rishnan, A. Abraham, T. Balasubramaniyan // Indian
J. Nephrol. - 2013. - Vol. 23(4). - P. 308-311.
47. Alexander MP. Membranous glomerulonephritis is a manifestation of IgG4-related disease / MP.Alexander, CP.Larsen, IW.Gibson //Kidney Int. - 2013. - Vol. 83(3). - P. 455-462.
48. Kawano M. Proposalfor diagnostic criteria forIgG4- related kidney disease /M.Kawano, T.Saeki, H.Nakashima, S.Nishi, Y.Yamaguchi, S.Hiscmo//Clin. Exp. Nephrol. -2011. - Vol. 15. - P.615-626.
49. Tabata T. Serial changes of elevated serum lgG4 levels in IgG4-related systemic disease / T.Tabata, T.Kamisawa,
K. Takuma, et al. //Intern. Med. - 2011. - Vol. 50. - P. 69-75.
50. Khosroshahi A. Rituximab for the treatment of IgG4- related disease: lessons from ten consecutive patients /
A. Khosroshahi, M.Carruthers, VDeshpande, S.Unizony, DB.Bloch, JH.Stone // Medicine (Baltimore). - 2012. - Vol. 91. - P. 57-66.
С.В. Данилюк, О.Б. Ященко // Укр. Реем. Журнал. -2013,- №2 - С. 8-13.
2. Stone J.H. IgG4-related disease / John H. Stone, Yoh Zen, Vikram Deshpande // N Engl. J Med. - 2012. - Vol. 336. - P.539-561.
3. Stone JH. lgG4-related systemic disease and lymphoplasmacytic aortitis / JH Stone, A.Khosroshahi, A.Hilgenberg et al. // Arthritis Rheum. - 2009. - Vol. 60. - P.3139-3145.
4. Frulloni L. Identification of a novel antibody associated with autoimmune pancreatitis / L.Frulloni, C. Lunar di, R. Simone, et al. // N Engl. J Med. - 2009. - Vol.361. - P.2135-2142.
5. Nishimori I. Prevalence of autoimmune pancreatitis in Japan from a nationwide survey in 2002 /I. Nishimori, A. Tama- koshi, M.Otsuki // J Gastroenterol. - 2007. - Vol.42. - P. 6-8.
6. Yamamoto M. Clinical and pathological differences between Mikulicz’s disease and Sjogren’s syndrome / M. Yamamoto, S. Harada, M. Ohara, et al // Rheumatology (Oxford) - 2005. - Vol.44. - P.227-234.
7. Stone J.H. Aortitis, retroperitoneal fibrosis, and lgG4-related disease / John H. Stone // La Presse Medicale. - 2013. - Vol.42. -P. 622-625.
8. Stone JH. lgG4-related systemic disease accounts for a significant proportion of thoracic lymphoplasmacytic aortitis cases / JH.Stone, A.Khosroshahi, VDeshpande, JR.Stone //Arthrit. Care Res.-2010. - Vol.62. -P. 316-322.
9. Stone J.H. Aortitis, periaortitis, and retroperitoneal fibrosis, as manifestations of lgG4-related systemic disea¬se / John H. Stone // Curr. Opin. Rheumatol. - 2011. - Vol.23(l). - P.88.
10. Kasashima S. A clinicopathologic study of immu¬noglobulin G4-related disease of the femoral and popliteal arteries in the spectrum of immunoglobulin G4-related periarteritis /S.Kasashima, A.Kawashima, M.Endo //Journal of Vascular Surgery. - 2010. - Vol.57. - P. 816-822.
11. Umehara H. Comprehensive diagnostic criteria for lgG4-relateddisease, 2011 /H. Umehara, K.Okazaki, Y. Ma- saki, et al //Mod. Rheumatol. - 2012. - Vol.22. - P.21-30.
12. Kamisawa T. Serum lgG4-negative autoimmune pancreatitis / T.Kamisawa, K.Takuma, T.Tabata, et al. //
J. Gastroenterol. -2011. - Vol.46. - P. 108-116.
13. Ebbo M. Pathologies associated with serum IgG4 elevation / M.Ebbo, A. Grades, E.Bernit, et al. // Int.
J. Rheumatol. - 2012. - Vol. 64. - P. 602-613.
14. Carruthers M. Diagnosyic utility of serum IgG4 concentration in lgG4-related disease [Abstract] / M.Carruthers, T.Augustin, JH.Stone, A.Khosroshahi // Arthritis Rheum 2012.
15. Sah RP. Serologic issues in lgG4-related systemic disease and autoimmune pancreatitis /RP.Sah, ST.Chari // Curr. Opin. Rheumatol. - 2011. - Vol.23. - P. 108-113.
16. Hamano H. High serum IgG4 concentrations in patients with sclerosing pancreatitis. /H.Hamano, S.Kawa, A.Horiuchi, et al. // N. Engl. J. Med. - 2001. - Vol.334. - P.732-738.
17. Zen Y. Pathophysiology of IgG4-Related Disease / Y.Zen, Y.Nakanuma // Current Immunology Reviews. -2011. - Vol. 2. -P. 232-238.
lS.Kawa S. HLA DRB10405-DQB10401 haplotype is associated with autoimmune pancreatitis in the Japanese population / S.Kawa, M.Ota, K.Yoshizawa, et al. // Gastroenterology. - 2002. - Vol. 122. - P. 1264-1269.
19. Nirula A. What is IgG4? A review of the biology of a unique immunoglobulin subtype / A.Nirula, SM.Glaser, SL.Kalled, FR.Taylor // Curr. Opin. Rheumatol. - 2011. - Vol.23. -P. 119-124.
20. Kiyama K. Serum BAFF and APRIL levels in patients with IgG4-related disease and their clinical significance / KKiyama, D.Kawabata, Y.Hosono, KKitagori, N. Yukawa, H.Yoshifuji, K. Omura, T.Fujii, T.Mimori//Arthritis Research & Therapy - 2012. - Vol. 14. - P. 86.
21. Kasashima S. A new clinicopathological entity ofIgG4- related inflammatory abdominal aortic aneurysm / S.Ka¬sashima, Y.Zen, A.Kawashima, M.Endo, YMatsumoto, F.Ka- sashima // J. Vase. Surg.-2009. - Vol.49 (5). -P. 1264-1271.
22. Kasashima S. IgG4-related Inflammatory Abdominal Aortic Aneurysm, Spectrum of IgG4-related Chronic Periaortitis /S.Kasashima, Y.Zen //Ann. Vase. Dis. -2010. - Vol. 3(3). - P. 182-189.
23. Raparia K. Inflammatory aortic aneurysm: possible manifestation of IgG4-related sclerosing disease / KRaparia, C.P.Molina, G.Quiroga Garza, D.Weilbaecher, AG.Ayala, JY.Ro //Int. J. Clin. Exp. Pathol. -2013. - Vol.6 (3). - P. 469-475.
24. Mackay F. BAFF and APRIL: a tutorial on В cell survival / F.Mackay, P.Schneider, P.Rennert, J.Browning // Ann. Rev. Immunol. - 2003. - Vol.21. - P. 231-264.
25. Koike T. IgG4-related disease: why high lgG4 and fibrosis? / T.Koike //Arthritis. Res. Ther. - 2013. - Vol. 15 (1). - P. 103.
26. Kamisawa T. Allergic manifestations in autoimmune pancreatitis / T.Kamisawa, HAnjiki, N.Egawa, N.Kubota // Eur. J. Gastroentero. Hepatol. - 2009. - Vol.21. - P. 1136- 1139.
27. Li ZZ. Pathogenesis of Abdominal Aortic Aneurysms: Role of Nicotine and Nicotinic Acetylcholine Receptors / ZZ.Li, QY.Dai //Mediators Inflamm. - 2012. - Vol.2012. - P. 103-120.
28. Inoue D. Immunoglobulin G4-related periaortitis and periarteritis: CTfindings in 17patients/D.Inoue, Y.Zen, HAbo, T.Gabata//Radiology. -2011. - Vol.261. - P. 625-633.
29. Zen Y. IgG4-related disease: a cross-sectional study of 114 cases / Y.Zen, Y.Nakanuma //Am. J. Surg. Pathol. - 2010. - Vol. 34(12). -P. 1812-1819.
30. Sato Y. Systemic IgG4-related lymphadenopathy: a clinical and pathologic comparison to multicentric Castle¬man ’s disease / Y.Sato, M.Kojima, et al. // Mod/ Pathol. -
2009. - Vol. 22(4). - P. 589-599.
31. Cheuk W. IgG4-related sclerosing disease: a critical appraisal of an evolving clinicopathologic entity / W. Cheuk, JKChan // Adv. Anat. Pathol. - 2010. - Vol. 17(5). - P. 303-332.
32. Sato Y. Association between IgG4-related disease and progressively transformed germinal centers of lymph nodes /Y.Sato, D.Inoue, et al. //Mod. Pathol. - 2012. - Vol. 25(7).- P. 956-967.
33. Yamamoto M. Evaluation and Clinical Validity of a New Questionnaire for MikuliczIs Disease / M. Yamamoto, H. Takahashi, Kdshigami, H.Yajima, etal. //Int. J. Rheumatol. - 2012. - Vol. 2012. - P. 283-289.
34. Moriyama M. T helper subsets in SjogrenIs syndrome and IgG4-related dacryoadenitis and sialoadenitis: A cri¬tical review / M.Moriyama, A. Tanaka, T.Maehara, S. Furukawa, et al. // Journal of Autoimmunity xxx (2013) le8 (in press).
35. Dasari BV IgG4-related systemic sclerosing disease: a diagnosis to be considered / BVDasari, KMcElvanna, M.Loughrey, T.Diamond // BMJ Case Rep. - 2013. - doi: 10.1136/bcr-2012-007101.
36. Maehara T. Interleukin-21 contributes to germinal centre formation and immunoglobulin G4 production in IgG4-related dacryoadenitis and sialoadenitis, so-called Mikulicz Is disease / T.Maehara, MMoriyama, H.Nakashima,
K.Miyake, JN.Hayashida, A.Tanaka, et al. //Ann. Rheum. Dis. - 2012. - Vol. 71. - P. 2011-2020.
37.Sah R.P. Differences in clinical profile and relapse rate of type 1 versus type 2 autoimmune pancreatitis. Gastroenterology /RP.Sah, STChari, R.Pannala, et al. // -
2010. - Vol. 139(1).-P. 140-148.
38. Hardacre JM. Results of pancreaticoduodenectomy for lymphoplasmacytic sclerosing pancreatitis / JM.Hardacre, CA.Iacobuzio-Donahue, TA.Sohn, et al. // Ann. Surg. - 2003. - Vol. 237. - P. 853-859.
39. Bateman AC, Deheragoda MG. IgG4-related systemic sclerosing disease-an emerging and under¬diagnosed condition. Histopathology. - 2009. - Vol. 55. - P. 373-383.
40. Ghazale A. Value of serum lgG4 in the diagnosis of autoimmune pancreatitis and in distinguishing it from pancreatic cancer /A.Ghazale, ST.Chari, TC.Smyrk, etal. // Am J Gastroenterol. - 2007. - Vol. 102(8). - P. 1646-1653.
41. Hennessey JV. Riedel’s Thyroiditis: A Clinical Review / JVHennessey // J. Clin, Endocrinol, Metab. - 2011. - Vol. 96(10). - P. 3031-3041.
42. Divatia M. IgG4-Related Sclerosing Disease, an Emerging Entity: A Review of a Multi-System Disease / M. Divatia, S.A.Kim, J. Y.Ro // Yonsei Med. J. - 2012. - Vol. 53(1). -P. 15-34.
43. Taniguchi T. Interstitial pneumonia associated with autoimmune pancreatitis / T.Taniguchi, M.Ko, SSeko, et al. // Gut. - 2004. - Vol. 53(5). - P. 770-771.
44. Zen Y. IgG4-positive plasma cells in inflammatory pseudotumor (plasma cell granuloma) of the lung / Y.Zen, S.Kitagawa, H.Minato, et al. //Hum. Pathol. - 2005. - Vol. 36(7). -P. 710.
45. Inoue D. Immunoglobulin G4-related lung disease: CT findings with pathologic correlations / D.Inoue, Y.Zen, HAbo, et al. //Radiology. - 2009. - Vol. 251. - P. 260.
46. Gopalakrishnan N. lgG4 related interstitial nephritis: A case report and review of literature / N. Gopalak¬rishnan, A. Abraham, T. Balasubramaniyan // Indian
J. Nephrol. - 2013. - Vol. 23(4). - P. 308-311.
47. Alexander MP. Membranous glomerulonephritis is a manifestation of IgG4-related disease / MP.Alexander, CP.Larsen, IW.Gibson //Kidney Int. - 2013. - Vol. 83(3). - P. 455-462.
48. Kawano M. Proposalfor diagnostic criteria forIgG4- related kidney disease /M.Kawano, T.Saeki, H.Nakashima, S.Nishi, Y.Yamaguchi, S.Hiscmo//Clin. Exp. Nephrol. -2011. - Vol. 15. - P.615-626.
49. Tabata T. Serial changes of elevated serum lgG4 levels in IgG4-related systemic disease / T.Tabata, T.Kamisawa,
K. Takuma, et al. //Intern. Med. - 2011. - Vol. 50. - P. 69-75.
50. Khosroshahi A. Rituximab for the treatment of IgG4- related disease: lessons from ten consecutive patients /
A. Khosroshahi, M.Carruthers, VDeshpande, S.Unizony, DB.Bloch, JH.Stone // Medicine (Baltimore). - 2012. - Vol. 91. - P. 57-66.
Опубліковано
2013-09-25
Як цитувати
Петелицька, Л. Б., & Юр’єва, Г. О. (2013). IGG4 - АСОЦІЙОВАНІ ЗАХВОРЮВАННЯ - НОВА КЛАСИФІКАЦІЙНА ОДИНИЦЯ В РЕВМАТОЛОГІЇ. Український науково-медичний молодіжний журнал, 3(75), 33-38. вилучено із http://mmj.nmuofficial.com/index.php/journal/article/view/738
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