Characterization of anxiety level as a prognostic criterion for evaluating clinical outcomes of sleeve gastrectomy

Keywords: Sleeve Gastrectomy, Obesity, Anxiety, Metabolic Bariatric Surgery, Postoperative Period, psychoemotional disorders

Abstract

studying the impact of the mental health component in patients with obesity on the clinical outcomes of metabolic bariatric intervention is a relevant task of modern medicine that requires further study. To characterize the anxiety level of patients in the long-term period after sleeve gastrectomy and its prognostic value for determining the clinical outcomes of metabolic bariatric intervention. We analyzed the clinical treatment outcomes of 93 patients with obesity who underwent sleeve gastrectomy for the period 2018-2022. The group included 69 (74.19%) women and 24 (25.81%) men. The average age of the subjects was 42.20±11.09 years. The initial BMI of the subjects was 46.23±7.65 kg/m². Obesity staging was performed by calculating BMI (Quetelet, 1832). To characterize the clinical outcome of sleeve gastrectomy, we used the Swiss-Finnish BARIatric metabolic outcome score (SF-BARI Score) with an additional assessment of quality of life using the Moorehead-Ardelt QoL Questionnaire. For anxiety characterization, the GAD-7 (Generalized Anxiety Disorder) questionnaire was used. Differences were considered significant at p<0.05. The total clinical result of sleeve gastrectomy corresponded to very good values – 129.77±28.07 points. In 29 (31.18%) individuals, excellent clinical indicators were established, in 38 (40.86%) examined – very good, in 20 (21.51%) – good, in 6 (6.45%) – satisfactory (5 (5.38%) – poor + 1 (1.07%) – suboptimal). Analyzing the severity of anxiety disorder in the examined, the average total result according to the GAD-7 questionnaire was 6.29±5.43 points and corresponded to a mild level of anxiety. In patients with a higher level of anxiety, established by the GAD-7 questionnaire, significantly worse clinical results of sleeve gastrectomy in the long-term postoperative period were proven, confirmed by the presence of a strong inverse correlation between the indicators (τ=-0.76, p<0.00001). The high prognostic value of patient anxiety indicators regarding the determination of clinical results of sleeve gastrectomy in the long-term period has been proven. In particular, the presence of a minimal level of anxiety in the examined is associated with significantly higher chances of forming excellent treatment results (OR=12.50, CI (3.36-46.51), p=0.000004), while significantly higher chances of forming satisfactory results of sleeve gastrectomy were recorded in patients with a high level of anxiety (OR=140.00, CI (11.85-1654.42), p=0.000002). Thus, the high clinical effectiveness of sleeve gastrectomy in treating patients with obesity and the high prognostic value of anxiety indicators for determining the clinical outcomes of metabolic bariatric intervention have been proven. An integral component of improving the effectiveness of treatment, we consider a comprehensive multidisciplinary approach that includes not only body weight control but also assessment of the psychoemotional state of patients after metabolic bariatric intervention.

References

Naumova, L. V., Naumova, U. O., & Krytskyi, T. I. (2023). Body mass index as a key factor in life expectancy and methods of its correction. Achievements of Clinical and Experimental Medicine, (3), 13-18. https://doi.org/10.11603/1811-2471.2023.v.i3.14070.

Alma A, Marconi GD, Rossi E, Magnoni C, Paganelli A. Obesity and Wound Healing: Focus on Mesenchymal Stem Cells. Life. 2023;13(3):717. https://doi.org/10.3390/life13030717

Pestel J, Blangero F, Eljaafari A. Pathogenic Role of Adipose Tissue-Derived Mesenchymal Stem Cells in Obesity and Obesity-Related Inflammatory Diseases. Cells. 2023;12(3):348. https://doi.org/10.3390/cells12030348

. Boland L, Bitterlich LM, Hogan AE, Ankrum JA, English K. Translating MSC Therapy in the Age of Obesity. Front Immunol. 2022;13:943333. https://doi.org/10.3389/fimmu.2022.943333

Xia Q, Campbell JA, Ahmad H, Si L, de Graaff B, Palmer AJ. Bariatric surgery is a cost-saving treatment for obesity-A comprehensive meta-analysis and updated systematic review of health economic evaluations of bariatric surgery. Obes Rev. 2020;21(1):e12932. https://doi.org/10.1111/obr.12932

Alqifari AN, Alsaigh S, Al Harbi G, et al. Prevalence of Depression and Anxiety Among Post-bariatric Surgery Patients: A Cross-Sectional Study. Cureus. 2024;16(10):e72399. doi:10.7759/cureus.72399

Alshammari SA, Alassiri MA, Allami HA, Almousa HM, Alobaid AS, Ismail DH, et al. The Prevalence of Depression and Anxiety in Post-bariatric Surgery Patients at King Khalid University Hospital, Riyadh. Cureus. 2022;14(12):e32500. https://doi.org/10.7759/cureus.32500

RA, Alnujaidi MA. Prevalence and Outcomes of Depression After Bariatric Surgery: A Systematic Review and Meta-Analysis. Cureus. 2022;14(6):e25651. https://doi.org/10.7759/cureus.25651

Suliman O, Esailan MM, Alraddadi AM, Shaker AS, Alsharif LA, Aljohani MS, et al. The Prevalence and Consequence of Depression After Bariatric Surgery Among Adults in Saudi Arabia. Cureus. 2024;16(5):e59945. https://doi.org/10.7759/cureus.59945

By-Band-Sleeve Collaborating Group. Prevalence and short-term change in symptoms of anxiety and depression following bariatric surgery: a prospective cohort study. BMJ Open. 2024;14(1):e071231. https://doi.org/10.1136/bmjopen-2022-071231

Mittmann Gl, Schuhbauer M, Schrank B, Steiner-Hofbauer V. Effect of Bariatric Surgery on Anxiety Symptoms in Morbidly Obese Patients: A Systematic Narrative Literature Review. J Bariatric Surg. 2023;2(2):53-59. DOI: 10.4103/jbs.jbs_5_23

Paczkowska A, Hoffmann K, Raakow J, Pross M, Berghaus R, Michalak M, et al. Impact of bariatric surgery on depression, anxiety and stress symptoms among patients with morbid obesity: international multicentre study in Poland and Germany. BJPsych Open. 2022;8(1):e32. https://doi.org/10.1192/bjo.2021.1084

Ribeiro GANA, Giapietro HB, Belarmino LB, Salgado-Junior W. Depression, anxiety, and binge eating before and after bariatric surgery: problems that remain. Arq Bras Cir Dig. 2018;31(1):e1356. https://doi.org/10.1590/0102-672020180001e1356

Published
2025-09-29
How to Cite
1.
Pliuta I. Characterization of anxiety level as a prognostic criterion for evaluating clinical outcomes of sleeve gastrectomy. USMYJ [Internet]. 2025Sep.29 [cited 2026Mar.21];157(3):17-4. Available from: https://mmj.nmuofficial.com/index.php/journal/article/view/563