The importance of pharmaceutical care in the release of drugs for the prevention and treatment of acne in women
Abstract
acne vulgaris ranks third in the structure of dermatological diseases and is an urgent medical and social problem. The disease is often the cause of psycho-emotional disorders and contributes to the deterioration of patients' quality of life and social activity. However, the treatment of acne vulgaris is complex and long-term. This study aims to assess the role of pharmaceutical care in the release of drugs to prevent and treat acne in women. An anonymous survey of 100 teenage girls and women of different ages on a single specially designed questionnaire, considering the problems of acne treatment. Methods of an anonymous questionnaire survey, computer data processing, and graphics are used. It was found that the majority (82 %) of respondents considered the treatment of acne vulgaris to be problematic. In addition, only 36 % of respondents sought medical help, while the majority resorted to self-medication. The main drugs of choice were salicylic (42 %) and azelaic acids (38 %), clindamycin (24 %), benzoyl peroxide (11 %), and isotretinoin (10 %). In most cases (58 %) complex therapy was used. In addition, almost 60 % of respondents used sorbents during the treatment of acne vulgaris, and almost 20 % - combined oral contraceptives. Most respondents reported improvement after the end of treatment (57 %) and at least a week of therapy (29 %). It is important to note that 38 % of respondents noted the occurrence of adverse side effects with anti-acne drugs, the most common of which were: dry skin (68.7%), redness (56.3 %), increased rash (25.0 %), and itching (20.8 %). In addition, most respondents (80 %) did not observe facial hygiene and tried to "squeeze" acne vulgaris. At the same time, only half of the respondents received recommendations on the regime and rules for the use of anti-acne drugs from pharmacists. While within the framework of pharmaceutical care, pharmacists identify threatening conditions that require medical attention, provide recommendations on the rules and mode of use of over-the-counter drugs, and carry out informational and educational work on facial hygiene, dietary modifications, and non-drug measures. Therefore, given the high prevalence of self-medication, the use of several drugs, the importance of following the rules of skin hygiene, and providing quality pharmaceutical care are necessary for achieving the most effective and safe treatment of acne.
References
Бочарова В. В. (2018). Детермінантні складові стресової реакції у патогенезі вугрової хвороби. Досягнення біології та медицини, 31(1), 22–26.
Герасименко О. І. (2020). Роль гігієни обличчя у попередженні розвитку акне. International Forum: Problems and Scientific Solutions., 34(1), 529–531.
Державний експортний центр МОЗ України. (2017). Акне: Клінічна настанова заснована на доказах. https://www.dec.gov.ua/wp-content/uploads/2019/11/akn_akne.pdf.
Комаріда О. О., Бабенко М. М., & Лобас М. В. (б. д.). Протокол фармацевта при відпуску лікарських засобів без рецепта «Профілактика та лікування вугрів». https://www.dec.gov.ua/mtd/protokoly-farmaczevta.
Математическая обработка и анализ медико-биологических данных. (2018). Мединформ.
Місюрьова С. В., & Пропіснова В. В. (2018). Принципи фармацевтичної опіки при вугровій хворобі. Матеріали “Міжнародної науково-практичної конференції Сучасні методи корекції проблем шкіри у практиці косметолога", 147–148.
Перепічка М. П. (2019). Комплексне лікування вугрів вульгарних із застосуванням біотину. Журнал дерматовенерології та косметології імені М.О. Торсуєва., 42(2), 72–77.
Поліон Н. М., & Дюдюн А. Д. (2018). Деякі аспекти актуальності вугрової хвороби. Дерматовенорологія. Косметологія. Сексопатологія., 4(1), 72–77.
Свердан П. Л. (1998). Вища математика. Аналіз інформації у фармації та медицині : підручник. Львів : Світ. 332 с
Akpinar Kara, Y., & Ozdemir, D. (2019). Evaluation of food consumption in patients with acne vulgaris and its relationship with acne severity. Journal of Cosmetic Dermatology, 19(8), 2109–2113. https://doi.org/10.1111/jocd.13255.
Baldwin, H., & Tan, J. (2020). Effects of diet on acne and its response to treatment. American Journal of Clinical Dermatology. https://doi.org/10.1007/s40257-020-00542-y.
Bezeha O., Vasylyeva K., Yemchenko Y., & Oliynichenko Y. (2021). Ефективність застосування ретиноїдів першого покоління в лікуванні акне третього та четвертого ступеня тяжкості для покращення емоційного стану. Актуальні проблеми сучасної медицини: Вісник Української медичної стоматологічної академі, 21(4), 15–19.
Cong, T.-X., Hao, D., Wen, X., Li, X.-H., He, G., & Jiang, X. (2019). From pathogenesis of acne vulgaris to anti-acne agents. Archives of Dermatological Research, 311(5), 337–349. https://doi.org/10.1007/s00403-019-01908-x.
Damiani, G., Gironi, L. C., Grada, A., Kridin, K., Finelli, R., Buja, A., Bragazzi, N. L., Pigatto, P. D. M., & Savoia, P. (2021). COVID‐19 related masks increase severity of both acne (maskne) and rosacea (mask rosacea): Multi‐center, real‐life, telemedical, and observational prospective study. Dermatologic Therapy, 34(2). https://doi.org/10.1111/dth.14848.
Dréno, B. (2017). What is new in the pathophysiology of acne, an overview. Journal of the European Academy of Dermatology and Venereology, 31, 8–12. https://doi.org/10.1111/jdv.14374.
Dréno, B., Dagnelie, M. A., Khammari, A., & Corvec, S. (2020). The skin microbiome: A new actor in inflammatory acne. American Journal of Clinical Dermatology, 21(S1), 18–24. https://doi.org/10.1007/s40257-020-00531-1.
Dréno, B., Pécastaings, S., Corvec, S., Veraldi, S., Khammari, A., & Roques, C. (2018). Cutibacterium acnes(Propionibacterium acnes) and acne vulgaris: A brief look at the latest updates. Journal of the European Academy of Dermatology and Venereology, 32, 5–14. https://doi.org/10.1111/jdv.15043.
Farrukh Farhan Afzal, Sania Ahmad, Muhammad Younas Mehrose, Muhammd Saleem, Muhammad Amin Yousaf, Abdul Malik Mujahid, aif Ur Rehman, & Moazzam Nazeer Tarar. (2019). Efficacy оf micro-needling on post-acne scars. Journal of Ayub Medical College, 31(3), 336–339.
Heng, A. H. S., & Chew, F. T. (2020). Systematic review of the epidemiology of acne vulgaris. Scientific Reports, 10(1). https://doi.org/10.1038/s41598-020-62715-3.
Jennifer Athay Adams, Alex J. Adams, & Michael E. Klepser. (2021). Pharmacist prescriptive authority for acne: An evidence-based approach to policy. Pharmacy Practice, 12(2). https://doi.org/10.24926/iip.v12i2.3897.
Kwon, H., Yoon, J., Hong, J., Jung, J., Park, M., & Suh, D. (2012). Clinical and histological effect of a low glycaemic load diet in treatment of acne vulgaris in korean patients: A randomized, controlled trial. Acta Dermato Venereologica, 92(3), 241–246. https://doi.org/10.2340/00015555-1346.
Marron, S. E., Chernyshov, P. V., & Tomas-Aragones, L. (2019). Quality-of-Life research in acne vulgaris: Current status and future directions. American Journal of Clinical Dermatology, 20(4), 527–538. https://doi.org/10.1007/s40257-019-00438-6.
Oge L. K., Broussard A., & Marshall M. D. (2019). Acne vulgaris: Diagnosis and treatment. American Family Physician., 100(8), 475–484.
Salamzadeh, J., Torabi Kachousangi, S., Hamzelou, S., Naderi, S., & Daneshvar, E. (2020). Medication adherence and its possible associated factors in patients with acne vulgaris: A cross‐sectional study of 200 patients in Iran. Dermatologic Therapy, 33(6). https://doi.org/10.1111/dth.14408.
Sevimli Dikicier, B. (2019). Topical treatment of acne vulgaris: Efficiency, side effects, and adherence rate. Journal of International Medical Research, 47(7), 2987–2992. https://doi.org/10.1177/0300060519847367.
Xu, S., Zhu, Y., Hu, H., Liu, X., Li, L., Yang, B., Wu, W., Liang, Z., & Deng, D. (2021). The analysis of acne increasing suicide risk. Medicine, 100(24), Стаття e26035. https://doi.org/10.1097/md.0000000000026035.
Yousaf, A., Hagen, R., Delaney, E., Davis, S., & Zinn, Z. (2020). The influence of social media on acne treatment: A cross‐sectional survey. Pediatric Dermatology, 37(2), 301–304. https://doi.org/10.1111/pde.14091.
Yu, Y., Dunaway, S., Champer, J., Kim, J., & Alikhan, A. (2020). Changing our microbiome: Probiotics in dermatology. British Journal of Dermatology, 182(1), Стаття e28-e28. https://doi.org/10.1111/bjd.18659.

This work is licensed under a Creative Commons Attribution 4.0 International License.
ISSN
ISSN 














